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A closer look at the hospital
Two-year progression-free survival of 88% versus 63% is a concrete result from Ruijin’s GUIDANCE-01 randomized phase II trial, published in 2023. The study enrolled 128 patients with newly diagnosed intermediate- or high-risk diffuse large B-cell lymphoma, comparing genetically matched targeted drugs added to R-CHOP with standard R-CHOP. It illustrates the team’s focus on turning molecular diagnosis into treatment choices.
Leukemia is another defining strength. Zhenyi Wang, Zhu Chen, Saijuan Chen and colleagues made major contributions to all-trans retinoic acid and arsenic treatment for acute promyelocytic leukemia (APL). A 2017 Shanghai Jiao Tong medical school account described long-term disease-free survival above 95% in low- and intermediate-risk APL. This specific leukemia subtype demonstrates the service’s history of translating disease biology into effective treatment.
Ruijin’s hematologic oncology work now spans lymphoma, leukemia, CAR-T and other cellular treatments, supported by pathology, molecular classification and intensive-care expertise. Patients can seek teams matched to their subtype and treatment stage, including initial therapy and options after relapse.
For solid tumors, gastrointestinal minimally invasive surgery, pancreatic disease and integrated breast cancer care are important specialties. Endocrinology, infectious diseases, nutrition and intensive care support patients with complex treatment needs.
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Clinical strengths
Leukaemia classification and treatment
Ruijin’s haematology service and the Shanghai Institute of Hematology have longstanding work in leukaemia biology, classification and treatment. Leukaemia includes distinct diseases: marrow appearance, immunophenotype, chromosomes and molecular features refine the diagnosis and affect treatment expectations. The programme’s research tradition connects laboratory findings with clinical care.
Blood counts, marrow findings and residual disease help track response. In relapsed or refractory disease, reviewing the original subtype, responses and subsequent evolution supports assessment of further medicines, transplantation or other treatment.
Lymphoma: translating genetic subtypes into drug choices
In GUIDANCE-01, R-CHOP-X added targeted agents according to genetic subtype rather than giving every patient the same extra drug. Complete response was 88% versus 66% with standard R-CHOP, complementing the progression-free survival results above.
This is phase II evidence for newly diagnosed intermediate- or high-risk diffuse large B-cell lymphoma. Other lymphoma subtypes, relapsed disease and CAR-T treatment have their own evidence and assessment pathways.
CAR-T and support for intensive treatment
Ruijin reports clinical CAR-T work with multidisciplinary support. Suitability for a product or study depends on the disease, previous treatments and current health. Ask about assessment, cell collection, manufacturing, admission and observation after treatment.
Gastrointestinal surgery and minimally invasive techniques
Ruijin has a longstanding minimally invasive gastrointestinal surgery program. Minhua Zheng’s team has helped develop laparoscopic radical surgery for gastric and colorectal cancers, alongside clinical research, training and technical standards.
Surgical planning combines cancer clearance and lymph node management with disease extent, prior treatment and general fitness. Medical oncology, nutrition and recovery services contribute to the wider pathway.
Pancreatic surgery and translational research
Baiyong Shen’s pancreatic team combines longstanding clinical work, minimally invasive surgery and translational research. Its approach connects diagnosis, preoperative assessment, surgery, postoperative management and recurrence care. Vascular involvement, nutrition and biliary or pancreatic obstruction can all affect planning.
The team also studies approaches such as TCR-T and cancer vaccines. These are research programs; an individual patient’s access depends on an active study and eligibility.
Integrated breast cancer services
Ruijin’s breast center brings together breast surgery, radiation and medical oncology, pathology, radiology and ultrasound. Breast specialists including Kunwei Shen and Xiaosong Chen work alongside radiation experts such as Jiayi Chen.
Collaboration starts with imaging and tissue diagnosis and continues through treatment selection, nursing and rehabilitation. Tumor subtype and stage inform the sequence of surgery, medication and radiotherapy.
Endocrinology and endocrine tumor assessment
Endocrinology is a defining Ruijin specialty. Academician Guang Ning, Weiqing Wang and colleagues have longstanding work in diabetes, metabolism and adrenal disease. In adrenal lesions and related endocrine disorders, hormone assessment may be as important as imaging.
The service is also relevant when diabetes or treatment-associated endocrine abnormalities complicate cancer care, with collaboration among endocrine, surgical, imaging and laboratory teams.
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Specialists & clinical teams
Weili Zhao
Molecularly guided lymphoma treatment
Zhao’s team led GUIDANCE-01, a randomized phase II trial in 128 patients with newly diagnosed intermediate- or high-risk diffuse large B-cell lymphoma. Genetically matched additions to R-CHOP produced an 88% complete response rate versus 66% with R-CHOP alone. The practical focus is whether the lymphoma’s biology warrants a different regimen; treatment decisions still require confirmatory evidence and assessment of the patient’s fitness.
View supporting sourceJunmin Li
AML in older patients or those unable to receive intensive chemotherapy
For patients unable to tolerate intensive chemotherapy, Li’s clinical work includes the Chinese cohort of a phase III trial of venetoclax plus low-dose cytarabine in previously untreated AML. This focus is relevant to balancing leukemia control against marrow suppression and infection risk, and selecting treatment that matches the patient’s physical condition.
View supporting sourceBaiyong Shen
Minimally invasive pancreatic surgery and recovery
Shen’s team led PORTAL, a 268-patient phase III trial published in the BMJ in 2026. Median postoperative stay was 13 days after robotic pancreatoduodenectomy versus 16 after open surgery, although robotic surgery cost more. This expertise is relevant to resectable pancreatic-head or periampullary disease when weighing surgical burden, recovery and cost in an experienced center.
View supporting sourceStudy results describe selected patient groups, not an individual doctor’s success rate. Availability, case acceptance and the treating team require hospital confirmation.
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Your international care journey
Send pathology or marrow findings, all prior treatment lines and a recent clinical update to establish the appropriate haematology service. CAR-T enquiries should clarify acceptance criteria and timing before planning a stay, caregiver support and follow-up in Shanghai.
Share your records and questions
Send the diagnosis, pathology, imaging and treatment history. Explain whether you want a second opinion, information about a treatment or an in-person visit. We help organise the records and identify missing information.
Confirm the specialty and acceptance
The relevant service confirms whether it can accept the case and whether pathology review or more records are needed. The hospital determines whether remote assessment or a multidisciplinary opinion is appropriate.
Agree appointments, costs and travel
Confirm the campus, first appointment, proposed assessment and payment requirements before arranging visas, accommodation, transport and interpreting. Discuss caregivers and length of stay when repeated treatment is expected.
Attend assessment and discuss the plan
The clinicians assess the case, arrange necessary tests and explain suitable options, expected benefits and risks. Discuss costs and logistics alongside the clinical plan before deciding on the next step.
Stay informed during treatment
Agreed support can include appointments, interpreting and communication during care. Keep track of questions and clinical feedback, and review schedules, costs and family arrangements if the treatment plan changes.
Return home with a follow-up plan
Before departure, collect the discharge summary, pathology and imaging, medicines and follow-up plan. Clarify pending reports and contact arrangements, with support for communication between local and treating clinicians where agreed.
What to prepare for the first enquiry
For blood cancers, include marrow, flow cytometry, cytogenetic and molecular results and available residual disease assessments. Gastrointestinal or pancreatic cases need endoscopy, contrast imaging and operative records; breast cases need receptor and HER2 results. Provide a dated treatment history and information on underlying conditions.
Diagnosis & pathology
Diagnosis summary, complete pathology, immunohistochemistry, available molecular tests and where tissue is held.
Original imaging
Recent and pretreatment imaging studies with reports and dates, so changes can be compared.
Treatment timeline
Operations, radiotherapy plans, each drug regimen, responses and major side effects; current medicines and allergies.
Your practical needs
Home country, preferred language, possible travel dates, caregiver needs and the questions you want answered.
Start with the records you already have. We can help identify gaps; do not arrange additional tests solely to make an enquiry.
See the full records checklistPractical details to settle before travel
Costs & payment
Ask what the hospital estimate includes, deposits, additional charges and refund arrangements. Plan travel and living costs separately. Insurance coverage and direct billing require confirmation.
Language & records
Confirm interpreting for appointments, communication during treatment and the language of records. Our China coordination includes Chinese and English support; other languages need advance confirmation of availability and arrangements.
Campus, accommodation & caregivers
Consultations, tests and admission may take place at different sites. Distance, accessibility, caregiver rules and follow-up frequency all affect the itinerary and should be considered once the clinical plan is clearer.
Length of stay & returning home
Assessment, surgery, radiotherapy and cellular treatment have different schedules. Ask the hospital for the expected course, allowing for results and changes in the plan. Confirm readiness to return home with the clinical team.
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How Chirona can help
From organising records and contacting an appropriate specialty to travel in China and follow-up at home, we help connect the practical steps. Tell us the diagnosis, treatment so far and the question you most want answered.
Make your history easier to review
Organise treatments and key reports, help with necessary translation and bring the important questions to the clinician.
Find the appropriate clinical service
Enquire with the relevant specialty, follow up on record requirements and help clarify acceptance and appointments.
Coordinate the practical steps in China
Within the agreed scope, help with visa documentation, travel, arrival transport, accommodation and accompaniment.
Keep communication connected
Help organise consultation feedback, records for home and follow-up requirements, with continued contact as agreed.
The hospital and clinicians make diagnostic, treatment and acceptance decisions. Chirona provides consultation and care coordination within the agreed scope.
Explore our service process06
Questions before you decide
Is the latest marrow report enough?
The team will also need the original classification, molecular results, treatment history and changes in residual disease. A dated record shows how the disease evolved and which treatments worked or stopped working.
Can I request one of the specialists featured here?
Tell us your preference and we can help enquire. The hospital confirms acceptance, the specialist’s involvement and who provides outpatient or inpatient care. It may also recommend another suitable clinician within the specialty.
Can I contact Chirona before choosing a hospital?
Yes. Share the diagnosis, treatment history and the decision you need help with. We can organise the questions to consider when comparing hospitals and explain the coordination available.
Does submitting records confirm treatment?
Submitting records starts the assessment. The hospital must confirm acceptance and clinical suitability and may require more information or in-person tests. Appointment confirmation, the treatment plan and costs should be clarified separately.
Sources & further reading
Profiles draw on the institutional sources below, including historical material where it explains a programme’s development. Appointments, services and research recruitment can change and need confirmation when enquiring.
- Shanghai Jiao Tong University: Ruijin haematology
- Shanghai Jiao Tong University: lymphoma and CAR-T work
- Institution & specialty information · shsmu.edu.cn
- Clinical programmes & patient services · shsmu.edu.cn
- Minimally invasive gastrointestinal surgery
- Pancreatic program and Baiyong Shen (2025)
- Breast disease center
- Endocrinology and metabolism
- Breast specialty development (2023)
- Weili Zhao
- SJTU medical school: long-term disease-free survival in low/intermediate-risk APL (2017)
- Junmin Li
- Baiyong Shen
